You can either use attenuated/weakened virus or inactivated/dead virus.
A modern way would be
to use Viral protein or Virus-like
particles.
The current cutting-edge method is to use Virus genetic
material.
You must first conduct Serial testing to determine the right sort of
vaccine.
You have a choice of genetic materials, either go with DNA or RNA. You can send them on their own or by hitching a ride on another virus.
You will need a high-safety biolab to culture the virus.
Although the odds are small, even a weakened virus may mutate inside the body.
You can see how this Live Attenuated Virus vaccine works.
You will need a lab with high biological safety.
This kind of vaccine has a lower chance of inducing immunity, compared to the ones made using weakened virus.
You may choose to first evaluate this inactivated vaccine vaccine development method.
Protein is susceptible to damage when circulating in our body.
Protein-based vaccine is not easily recognizable by our immune system.
Protein-based vaccine usually requires more than one injection.
You are either seriously looking into this technique, known as the Protein Subunit Vaccine.
You must somehow construct virus-like particles. This is awfully complicated.
You can take a look at how the Virus Like Particle technique works.
Before your vaccine is seen as fit for production and distribution, it has to undergo these 5 stages
PRECLINICAL TRIAL
In this early stage, your vaccine are to be tested on animals, like lab rats. Then evaluate wheter or not they successfully induce immunity.
PHASE I CLINICAL TRIAL
Here you o a limited test of your vaccines to a group of randomly selected individuals. The goal is to see if your vaccines have some potentially dangerous side effects. Please remember to do the test only on healthy persons.
PHASE II CLINICAL TRIAL
Now the test gets bigger, involving hundreds of people from diffrent demographics, including the elderly, children, and members of vulnerable groups. You still keep a close eye on safety, and try to determine the appropriate dose.
PHASE III CLINICAL TRIAL
It gets even bigger, with thousands people now involved. You give the actual vaccine to some, and dummy ones to some others for a placebo effect. Then you compare the results to see how well the vaccines really go.
APPROVAL
If your vaccine is medically proven to be effective, a regulatory body will give approval for its use.
This process may be accelerated during a pandemic like now.
This process may be accelerated during a pandemic like now.
Trials for each phase may be conducted simultaneously to save precious time.
Okay, now you can move on to the strategy.
DNA is indeed more stable than RNA. But this technique is still in its infancy. Not one vaccine of this kind has actually been put to use. The stakes are high.
You can see how the DNA vaccine works.
This is bleeding edge technology. Not one vaccine of this kind has actually been put to use. The stakes are high.
You can see how the RNA vaccine works.
This is very new stuff. Not one vaccine of this kind has actually been put to use.
There is a slight chance of mutation in the virus used as a delivery vehicle.
You can see how this Viral vector vaccine works.
